Beta-galaktozid transacetilaza
β-galaktozid transacetilaza je enzim koji vrši transfer acetil grupe sa acetil-KoA na β-galaktozide. Kodiran je genom (lacA) u lac operonu bakterije Escherichia coli.[1] Precisza funkcija ovog enzima u okviru lac operona trenutno nije poznata.[2] Njegova kinetika je razjašnjena 1995.[3]
Povezano
- Acetiltransferaza
Reference
- ↑ Wang XG; Olsen LR; Roderick SL. (April 2002). „Structure of the lac operon galactoside acetyltransferase”. Structure 10 (4): 581–8. DOI:10.1016/S0969-2126(02)00741-4. PMID 11937062.
- ↑ Roderick SL. (June 2005). „The lac operon galactoside acetyltransferase”. C R Biol. 328 (6): 568–75. DOI:10.1016/j.crvi.2005.03.005. PMID 15950163.
- ↑ A. Lewendon; J. Ellis, W.V. Shaw (1995). „Structural and Mechanistic Studies of Galactoside Acetyltransferase, the Escherichia coli LacA Gene Product”. J. Biol. Chem. 270 (44): 26326–31.. DOI:10.1074/jbc.270.44.26326. PMID 7592843.
Literatura
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
Vanjske veze
- MeSH galactoside+acetyltransferase
- EC 2.3.1.18
- p
- r
- u
Transferaze: aciltransferaze (EC 2.3)
acetiltransferaze: Acetil-koenzime A acetiltransferaza - N-acetilglutamat sintaza - Holinska acetiltransferaza - Dihidrolipoil transacetilaza - Acetil-KoA C-aciltransferaza - Beta-galaktozid transacetilaza - hloramfenikol acetiltransferaza - N-acetiltransferaza (Serotonin N-acetil transferaza, HGSNAT, ARD1A) - Histon acetiltransferaza (P300/CBP, NAT2)
palmitoiltransferaze: Karnitin O-palmitoiltransferaza (CPT1, CPT2) - Serin C-palmitoiltransferaza (SPTLC1, SPTLC2)
druge: Aciltransferazi slična 2 - Sintaza aminolevulinske kiseline - Beta-ketoacil-ACP sintaza - Gliceronfosfat O-aciltransferaza - Lecitin-holesterol aciltransferaza
Glicerol-3-fosfat O-aciltransferaza - 1-acilglicerol-3-fosfat O-aciltransferaza - 2-acilglicerol-3-fosfat O-aciltransferaza - ABHD5B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
