Acetiltransferaza

Hemijska struktura acetilne grupe vezane za ostatak (R) molekula.

Acetiltransferaza (transacetilaza) je tip enzima transferaza koji prenose acetil grupu.[1]

Primer acetiltransferaza su:

  • Histon acetiltransferaze, među kojima je CBP histonska acetiltransferaza[2][3]
  • Holin acetiltransferaza[4][5]
  • Hloramfenikol acetiltransferaza
  • Serotonin N-acetil transferaza
  • NatA Acetiltransferaza
  • NatB akteiltransferaza

Povezano

  • Aciltransferaza

Reference

  1. Donald Voet, Judith G. Voet (2005). Biochemistry (3 izd.). Wiley. ISBN 978-0-471-19350-0. 
  2. Chrivia JC, Kwok RP, Lamb N, Hagiwara M, Montminy MR, Goodman RH (October 1993). „Phosphorylated CREB binds specifically to the nuclear protein CBP”. Nature 365 (6449): 855–9. Bibcode 1993Natur.365..855C. DOI:10.1038/365855a0. PMID 8413673. 
  3. Wydner KL, Bhattacharya S, Eckner R, Lawrence JB, Livingston DM (November 1995). „Localization of human CREB-binding protein gene (CREBBP) to 16p13.2-p13.3 by fluorescence in situ hybridization”. Genomics 30 (2): 395–6. PMID 8586450. 
  4. „Entrez Gene: CHAT choline acetyltransferase”. 
  5. Strauss WL, Kemper RR, Jayakar P, Kong CF, Hersh LB, Hilt DC, Rabin M (February 1991). „Human choline acetyltransferase gene maps to region 10q11-q22.2 by in situ hybridization”. Genomics 9 (2): 396–8. DOI:10.1016/0888-7543(91)90273-H. PMID 1840566. 

Literatura

  • Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X. 
  • Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036. 
  • Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0. 
  • Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097. 
  • Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X. 
  • Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842. 

Vanjske veze

  • MeSH Acetyltransferases
  • p
  • r
  • u
2.3.1: osim amino-acilne grupe2.3.2: Aminoaciltransferaze2.3.3: konverzija u alkil pri transferu
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
  • p
  • r
  • u
Teme
Tipovi
EC1 Oksidoreduktaze/spisak  • EC2 Transferaze/spisak  • EC3 Hidrolaze/spisak  • EC4 Lijaze/spisak  • EC5 Izomeraze/spisak  • EC6 Ligaze/spisak
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6