Trimerlizin I
| Trimerlizin I | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.24.52 | ||||||||
| CAS broj | 151125-16-5 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Trimerlizin I (EC 3.4.24.52, Trimeresurus metaloendopeptidaza I, hemoragična proteinaza HR1A, hemoragična metaloproteinaza HR1A, metaloproteinaza HR1A) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Razlaganje dve veze, His10-Leu i Ala14-Leu, u lancu insulina B
Ova hemoragična endopeptidaza je prisutna u venumu zmije Trimeresurus flavoviridis.
Reference
- ^ Omori-Satoh, T. & Sadahiro, S. (1979). „Resolution of the major hemorrhagic component of Trimeresurus flavoviridis venom into two parts”. Biochim. Biophys. Acta. 580: 392—404. PMID 518906.
- ^ Yamakawa, Y. & Omori-Satoh, T. (1988). „The sites of cleavage in oxidized insulin-B chain by a hemorrhagic protease derived from the venom of the habu (Trimeresurus flavoviridis)”. Toxicon. 26: 227—231. PMID 3284004.
- ^ Takeya, H., Oda, K., Miyata, T., Omori-Satoh, T. and Iwanaga, S. (1990). „The complete amino acid sequence of the high molecular mass hemorrhagic protein HR1B isolated from the venom of Trimeresurus flavoviridis”. J. Biol. Chem. 265: 16068—16073. PMID 2398046. CS1 одржавање: Вишеструка имена: списак аутора (веза)
Literatura
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
- Trimerelysin+I на US National Library of Medicine Medical Subject Headings (MeSH)
- п
- р
- у
| 3.4.11 | |
|---|---|
| 3.4.13 | Dipeptidaza (1, 2, 3) |
| 3.4.14 | Dipeptidil peptidaza (Katepsin C, Dipeptidil peptidaza-4) · Tripeptidil peptidaza (Tripeptidil peptidaza I, Tripeptidil peptidaza II) |
| 3.4.15 | |
| 3.4.16 | Karboksipeptidaze serinskog tipa: Katepsin A · DD-transpeptidaza |
| 3.4.17 | |
| Drugi/negrupisni | Metaloeksopeptidaza |
Serinske peptidaze · Cisteinska proteaza · Aspartatna proteaza · Metaloendopeptidaze
Druge/negrupisane: Sekretaza amiloidnog prekursornog proteina (Alfa-sekretaza, Beta-sekretaza 1, Beta-sekretaza 2, Gama sekretaza)
Druge/negrupisane: Sekretaza amiloidnog prekursornog proteina (Alfa-sekretaza, Beta-sekretaza 1, Beta-sekretaza 2, Gama sekretaza)
Stafilokinaza
B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
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