Sfingomijelinska fosfodiestaraza D
| Sfingomijelinska fosfodiestaraza D | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.4.41 | ||||||||
| CAS broj | 54992-31-3 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Sfingomijelinska fosfodiestaraza D (EC 3.1.4.41, sfingomijelinaza D) je enzim sa sistematskim imenom sphingomijelin keramid-fosfohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- sfingomijelin + H2O keramid fosfat + holin
Ovaj enzim ne deluje na fosfatidilholin, ali hidrolizuje 2-lizofosfatidilholin do holina i 2-lizofosfatidata.
Reference
- ^ Carne, H.R. & Onon, E. (1978). „Action of Corynebacterium ovis exotoxin on endothelial cells of blood vessels”. Nature. 271: 246—248. PMID 622164.
- ^ Soucek, A., Michalec, C. and Souckov, A. (1971). „Identification and characterization of a new enzyme of the group phospholipase D isolated from Corynebacterium ovis”. Biochim. Biophys. Acta. 227: 116—128. PMID 5543581. CS1 одржавање: Вишеструка имена: списак аутора (веза)
Literatura
- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
- Sphingomyelin+phosphodiesterase+D на US National Library of Medicine Medical Subject Headings (MeSH)
- п
- р
- у
- EC1 Oksidoreduktaze /spisak
- EC2 Transferaze /spisak
- EC3 Hidrolaze /spisak
- EC4 Lijaze /spisak
- EC5 Izomeraze /spisak
- EC6 Ligaze /spisak
- B enzm: 1.1/2/3/4/5/6/7/8/10/11/13/14/15-18, 2.1/2/3/4/5/6/7/8, 2.7.10, 2.7.11-12, 3.1/2/3/4/5/6/7, 3.1.3.48, 3.4.21/22/23/24, 4.1/2/3/4/5/6, 5.1/2/3/4/99, 6.1-3/4/5-6
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