TAOK1 |
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Identifiers |
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Aliases | TAOK1, KFC-B, MAP3K16, MARKK, PSK-2, PSK2, TAO1, hKFC-B, hTAO kinase 1, DDIB |
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External IDs | OMIM: 610266; MGI: 1914490; HomoloGene: 27041; GeneCards: TAOK1; OMA:TAOK1 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 17 (human)[1] |
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| Band | 17q11.2 | Start | 29,390,363 bp[1] |
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End | 29,551,903 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 11 (mouse)[2] |
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| Band | 11|11 B5 | Start | 77,419,988 bp[2] |
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End | 77,498,641 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - corpus callosum
- globus pallidus
- internal globus pallidus
- ventral tegmental area
- subthalamic nucleus
- sural nerve
- Pars compacta
- inferior ganglion of vagus nerve
- pons
- external globus pallidus
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| Top expressed in | - ventromedial nucleus
- lateral septal nucleus
- amygdala
- lateral geniculate nucleus
- olfactory tubercle
- anterior amygdaloid area
- mammillary body
- habenula
- inferior colliculus
- globus pallidus
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| More reference expression data |
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BioGPS | | More reference expression data |
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Gene ontology |
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Molecular function | - transferase activity
- protein kinase activity
- nucleotide binding
- kinase activity
- protein serine/threonine kinase activity
- protein binding
- ATP binding
- MAP kinase kinase kinase activity
- alpha-tubulin binding
- protein serine/threonine kinase activator activity
- tau protein binding
- beta-tubulin binding
- tau-protein kinase activity
| Cellular component | - cytoplasm
- cytosol
- extracellular exosome
- nucleus
- microtubule cytoskeleton
- perinuclear region of cytoplasm
| Biological process | - phosphorylation
- execution phase of apoptosis
- positive regulation of JNK cascade
- cellular response to DNA damage stimulus
- protein phosphorylation
- spindle checkpoint signaling
- regulation of cytoskeleton organization
- DNA repair
- positive regulation of stress-activated MAPK cascade
- apoptotic process
- sister chromatid cohesion
- MAPK cascade
- regulation of mitotic cell cycle
- nervous system development
- regulation of apoptotic process
- microtubule cytoskeleton organization
- negative regulation of microtubule depolymerization
- mitotic G2 DNA damage checkpoint signaling
- signal transduction
- stress-activated protein kinase signaling cascade
- activation of protein kinase activity
- regulation of actin cytoskeleton organization
- protein autophosphorylation
- neuron cellular homeostasis
- regulation of microtubule cytoskeleton organization
- positive regulation of protein acetylation
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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NM_144825 NM_001364133 NM_001364134 |
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RefSeq (protein) | | |
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NP_659074 NP_001351062 NP_001351063 |
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Location (UCSC) | Chr 17: 29.39 – 29.55 Mb | Chr 11: 77.42 – 77.5 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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