Subacute lymphocytic thyroiditis
Subacute lymphocytic thyroiditis | |
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Other names | Silent thyroiditis or Painless thyroiditis |
Specialty | Endocrinology |
Subacute lymphocytic thyroiditis is a form of thyroiditis. Subacute lymphocytic thyroiditis may occur at any age and is more common in females. A variant of subacute lymphocytic thyroiditis occurs postpartum: postpartum thyroiditis. Both of these entities can be considered subtypes of Hashimoto's thyroiditis and have an autoimmune basis. Anti-thyroid antibodies are common in all three and the underlying histology is similar. [1][2] This disorder should not be confused with de Quervain's thyroiditis which is another form of subacute thyroiditis.
Symptoms and signs
Subacute lymphocytic thyroiditis features a small goiter without tenderness. This condition tends to have a phase of hyperthyroidism followed by a return to a euthyroid state, and then a phase of hypothyroidism, followed again by a return to the euthyroid state. The time span of each phase can vary; however, each phase usually lasts 2–3 months.[1]
Diagnosis
Subacute lymphocytic thyroiditis can only be diagnosed correctly by taking a radioactive iodine uptake test (RAIU) test.[1][3] During both the hyperthyroid and hypothyroid phases, radioiodine uptake is decreased.[4] This situation contrasts greatly with the elevated iodine uptake found in patients with Graves' disease.[1]
Treatment
Treatment is based on symptoms. Beta-blockers relieve rapid heart rate and excessive sweating during the hyperthyroid phase.[4]
References
- ^ a b c d Thyroiditis: Differential Diagnosis and Management, American Family Physician, February 15, 2000
- ^ "Subacute lymphocytic thyroiditis" at Dorland's Medical Dictionary
- ^ Description of Radioactive Iodine Uptake Test, WebMD.com, August 14, 2008
- ^ a b NIH Medline Plus
- v
- t
- e
- Iodine deficiency
- Cretinism
- Congenital hypothyroidism
- Myxedema
- Myxedema coma
- Euthyroid sick syndrome
- Van Wyk-Grumbach syndrome
- Signs and symptoms
- Thyroid dyshormonogenesis
- Pickardt syndrome
- Hypothyroid myopathy
- KDSS
- Hoffmann syndrome
- LEMS
- Atrophic type
Graves' disease |
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- Acute infectious
- Subacute
- De Quervain's
- Subacute lymphocytic
- Palpation
- Autoimmune/chronic