SGPL1 |
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Available structures |
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PDB | Ortholog search: PDBe RCSB |
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Identifiers |
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Aliases | SGPL1, S1PL, SPL, sphingosine-1-phosphate lyase 1, NPHS14 |
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External IDs | OMIM: 603729; MGI: 1261415; HomoloGene: 2897; GeneCards: SGPL1; OMA:SGPL1 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 10 (human)[1] |
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| Band | 10q22.1 | Start | 70,815,948 bp[1] |
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End | 70,881,184 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 10 (mouse)[2] |
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| Band | 10 B4|10 32.14 cM | Start | 60,934,421 bp[2] |
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End | 60,983,482 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - skin of thigh
- gingival epithelium
- sural nerve
- ventricular zone
- skin of arm
- germinal epithelium
- islet of Langerhans
- secondary oocyte
- epithelium of nasopharynx
- ganglionic eminence
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| Top expressed in | - transitional epithelium of urinary bladder
- olfactory epithelium
- stroma of bone marrow
- gastrula
- decidua
- lip
- thymus
- jejunum
- granulocyte
- skin of external ear
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - protein binding
- catalytic activity
- lyase activity
- pyridoxal phosphate binding
- carboxy-lyase activity
- sphinganine-1-phosphate aldolase activity
| Cellular component | - integral component of membrane
- endoplasmic reticulum membrane
- membrane
- integral component of endoplasmic reticulum membrane
- endoplasmic reticulum
| Biological process | - fibroblast migration
- roof of mouth development
- luteinization
- Leydig cell differentiation
- estrogen metabolic process
- androgen metabolic process
- kidney development
- ceramide metabolic process
- regulation of multicellular organism growth
- lipid metabolism
- carboxylic acid metabolic process
- skeletal system morphogenesis
- sphingolipid biosynthetic process
- post-embryonic development
- fatty acid metabolic process
- female gonad development
- vasculogenesis
- nitrogen compound metabolic process
- spermatogenesis
- apoptotic signaling pathway
- platelet-derived growth factor receptor signaling pathway
- face morphogenesis
- apoptotic process
- sphingolipid metabolic process
- sphingolipid catabolic process
- hemopoiesis
- ameboidal-type cell migration
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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NM_009163 NM_001316673 NM_001316674 |
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RefSeq (protein) | | |
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NP_001303602 NP_001303603 NP_033189 |
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Location (UCSC) | Chr 10: 70.82 – 70.88 Mb | Chr 10: 60.93 – 60.98 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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