Ohmecarfentanil
Chemical compound
- CA: Schedule I
- DE: NpSG (Industrial and scientific use only)
- UK: Class A
- Methyl 1-(2-hydroxy-2-phenylethyl)-3-methyl-4-(N-propanoylanilino)piperidine-4-carboxylate
- 3R,4R: 10432482
- 3R,4S: 10071012
- 3R,4R: 8607909
- 3R,4S: 8246552
- 3R,4R: Interactive image
- 3R,4S: Interactive image
- 3R,4R: CCC(=O)N(C1=CC=CC=C1)[C@@]2(CCN(C[C@H]2C)CC(C3=CC=CC=C3)O)C(=O)OC
- 3R,4S: CCC(=O)N(C1=CC=CC=C1)[C@]2(CCN(C[C@H]2C)CC(C3=CC=CC=C3)O)C(=O)OC
InChI
- 3R,4R: InChI=1S/C25H32N2O4/c1-4-23(29)27(21-13-9-6-10-14-21)25(24(30)31-3)15-16-26(17-19(25)2)18-22(28)20-11-7-5-8-12-20/h5-14,19,22,28H,4,15-18H2,1-3H3/t19-,22?,25-/m1/s1
- Key:HVTQDIBOZUDMTH-PJHDFATGSA-N
- 3R,4S: InChI=1S/C25H32N2O4/c1-4-23(29)27(21-13-9-6-10-14-21)25(24(30)31-3)15-16-26(17-19(25)2)18-22(28)20-11-7-5-8-12-20/h5-14,19,22,28H,4,15-18H2,1-3H3/t19-,22?,25+/m1/s1
- Key:HVTQDIBOZUDMTH-CGPDNSSVSA-N
Ohmecarfentanil (RTI-4614-38), also known as Ohlofentanil, is a mu opioid receptor agonist from the class of fentanyl analogues which was found to be 30,000 times more potent than morphine in the rhesus monkey single dose suppression test.[1] This makes ohmecarfentanil, along with some closely related analogues, among the most potent opioid agonists known at this time, even surpassing lofentanil and ohmefentanyl.
See also
- Opioid potency comparison
References
- ^ Carroll FI, Lewin AH, Mascarella SW, Seltzman HH, Reddy PA (April 2021). "Designer drugs: a medicinal chemistry perspective (II)". Annals of the New York Academy of Sciences. 1489 (1): 48–77. Bibcode:2021NYASA1489...48C. doi:10.1111/nyas.14349. PMID 32396701. S2CID 218617085.
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